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动物科学与动物医学学院导师-李泽君
2017-01-18 11:02  

天津农学院硕士生导师简介

学科专业:预防兽医学

研究方向:分子病原与免疫学

一、个人简介

李泽君,男,1974年出生,汉族,中共党员,博士,研究员,禽病室主任,先后获科技部“创新人才推进计划”中青年科技创新领军人才、上海市领军人才、全国农业科研杰出人才等称号,目前担任农业部水禽新发病毒病快速诊断与预防技术研究创新团队的首席科学家、中国农业科学院动物流感病毒病原生态学创新团队首席科学家、中国农业科学院研究生院博士生导师、上海兽医研究所学术委员会委员、《中国动物传染病学报》编委、《Vaccine》、《Journal of Virology》、《Virology》、等杂志审稿专家。主要从事动物病毒性传染病的预防与控制的应用与基础研究,在国内外专业期刊上发表学术论文50余篇,其中SCI收录30余篇,累计被他人SCI论文引用达700余次。

二、工作学习简历

19939-19987月,内蒙古农业大学兽医学院,学士学位;

19989-20017月,内蒙古农业大学兽医学院,硕士学位;

20019-20047月,中国农业科学院研究生院,博士学位。

20047-20059月,中国农业科学院哈尔滨兽医研究所,助理研究员;

20059-20087月,美国威斯康星大学兽医学院,博士后;

20087--现在,中国农业科学院上海兽医研究所,研究员;

20131-现在,中国农业科学院上海兽医研究所,博士生导师。

 

(校外硕导或无可不写此部分)

 

三、教学工作

 

l本科课程:

l研究生课程 :

四、主要研究领域或方向

l研究领域: 动物病毒性传染病的预防与控制的应用与基础研究

l研究方向:动物流感病毒和水禽新发病毒性传染病的致病机理和防控技术研究

五、学术及科研项目

l 承担的主要科研及教改项目有:

1、动物流感病毒病原生态学研究,中国农业科学院创新工程项目,经费:240万元/年,主持;

2、促进禽流感病毒变异的因素自,然科学基金(面上)项目(31472206),经费:88万元,主持;

3. 鸭坦布苏病毒的传播与致病的分子机制,国家重点研发计划项目课题(2016YFD0500106),经费:650万元,主持;

4. 动物流感病毒重配机制及对生物学特性影响,国家重点研发计划项目子课题(2016YFD0500204),经费:155万元,主持;

项目名称,项目来源/类别,总金额,主持或其他。

l学术及教改论文63篇,SCI收录30篇。

主要学术论文:

1. H. ChenG. DengZ. LiG.TianY. LiP. Jiao, L. Zhang, Z. Liu, R.G. Webster, K. Yu. The evolution of H5N1 influenza viruses in ducks in SouthernChina.  Proc. Natl. Acad. Sci. USA, 2004, 101(28): 10452-10457 (Z. Li andG. Deng contributed equally).

2. Zejun Li, Hualan Chen, Peirong Jiao,Guohua Deng, Guobin Tian, Yanbing Li, Erich Hoffmann, Robert G. Webster, YumikoMatsuoka, Kangzhen Yu.  Molecular basis associated with replication ofduck H5N1 influenza viruses in a mammalian mouse model.  Journal ofVirology, 2005, 79: 12058–12064.

3. Zejun Li, Yongping Jiang, Peirong Jiao,Aiqin Wang, Fengju Zhao, Guobin Tian, Xijun Wang, Kangzhen Yu, Zhigao Bu andHualan Chen.  The NS1 Gene Contributes to the Virulence of H5N1 Avian InfluenzaViruses.  Journal of Virology, 2006, 8011115-11123.

4. Zejun Li, Tokiko Watanabe, Masato Hatta,Shinji Watanabe, Asuka Nanbo, Makoto Ozawa, Satoshi Kakugawa, MasayukiShimojima, Shinya Yamada, Gabriele Neumann, and Yoshihiro Kawaoka. Mutationalanalysis of conserved amino acids in the influenza A virus nucleoprotein.Journal of Virology, 2009, 83(9): 4153–4162.1.

5. Pixi Yan, Youshu Zhao, Xu Zhang, DaweiXu, Xiaoguang Dai, Qiaoyang Teng, Liping Yan, Jiewen Zhou, Xiwen Ji, ShumeiZhang, Guangqing Liu, Yanjun Zhou, Yoshihiro Kawaoka, Guangzhi Tong,  and ZejunLi. An infectious disease of ducks caused by a newly emerged Tembusu virusstrain in mainland China. Virology, 2011, 417 (1): 1-8. (Correspondingauthor).

6. Liping Yan, Pixi Yan, Jiewen Zhou, QiaoyangTeng, and Zejun Li. Establishing a TaqMan-Based Real-Time PCR Assay forthe Rapid Detection and Quantification of the Newly Emerged Duck Tembusu Virus.Virology Journal, 2011, doi:10.1186/1743-422X-8-464. (Correspondingauthor).

7. Liping Yan, Shan Peng, Pixi Yan, JiewenZhou, Qiaoyang Teng, Guoxin Li, Xuesong Li, Zejun Li. Comparison ofreal-time reverse transcription loop-mediated isothermal amplification andreal-time reverse transcription polymerase chain reaction for duck Tembusuvirus, Journal of virological methods, 2012, 182 (2012) 5055. (Corresponding author).

8. Yuee Zhang, Qiaoyang Teng, Chaochao Ren,Guoxin Li, Xuesong Li, and Zejun Li. 2012, Complete genome sequence of anovel reassortant H11N2 avian influenza virus isolated from a live poultrymarket in Eastern China.  Journal of Virology, 86 (22), 12443.(Corresponding author).

9. Qiaoyang Teng, Tao Hu, Xuesong Li,Guoxin Li and Zejun Li. 2012, Complete Genome Sequence of an H3N2 AvianInfluenza Virus Isolated from a Live Poultry Market in Eastern China. Journalof Virology, 86(21):11944. (Corresponding author).

10. Qiaoyang Teng, Xiwen Ji, Guoxin Li,Xuesong Li, and Zejun Li. 2012, Complete Genome Sequences of a NovelReassortant H4N2 Avian Influenza Virus Isolated from a Live Poultry Market inEastern China. Journal of Virology, 86(21):11952. (Correspondingauthor).

11. Qiaoyang Teng, Xu Zhang, Dawei Xu,Jiewen Zhou, Xiaoguang Dai, Zhaoguo Chen, Zejun Li. 2012,Characterization of an H3N2 canine influenza virus isolated from Tibetanmastiffs in China. Veterinary Microbiology. 1622-4):345-352 (Correspondingauthor).

12. Xuesong Li, Guoxin Li, Qiaoyang Teng,Zejun Li. 2012, Development of a Blocking ELISA for Detection of SerumNeutralizing Antibodies against Newly Emerged Duck Tembusu Virus. PLOS ONE. 7(12): e53026. (Corresponding author).

13. Li Guoxin, Gao Xuyuan, Xiao Yali, LiuShaoqqiong, Peng Shan, Li Xuesong, Shi Yin, Zhang Yuee, Yu Lei, Wu Xiaogang,Yan Pixi, Yan Liping, Teng Qiaoyang, Tong Guangzhi, Li Zejun.Development of a live attenuated vaccine candidate against duck Tembusu viraldisease. Virology, 450-451, PP233, 2014. (Corresponding author).

14. Li X, Shi Y, Liu Q, Wang Y, Li G, TengQ, Zhang Y, Liu S, Li Z. Airborne Transmission of a Novel Tembusu Virusin Ducks. J Clin Microbiol. 2015, 53(8):2734-6. (Corresponding author)

15. Teng Qiaoyang, Shen Weixia, LiuQinfang, Rong Guangyu, Chen Lin, Li Xuesong, Chen Hongjun, Yang Jianmei, LiZejun*. Protective efficacy of an inactivated vaccine against H9N2 avianinfluenza virus in ducks. Virology Journal, 2015, 17;12: 143, doi:10.1186/s12985-015-0372-7. (Corresponding author)

16. Teng QiaoYang, Shen WeiXia, Yan DaWei,Yan LiPing, Li XueSong, Li GuoXin, Yang JianMei, Li ZeJun*.Developmentof a TaqMan MGB RT-PCR for the rapid detection of H3 subtype avian influenzavirus circulating in China. Journal of Virological Methods. 2015, 217:64-69. (Corresponding author)

17. Yang J, Dai X, Chen H, Teng Q, Li X1,Rong G, Yan L, Liu Q, Li Z. Development of blocking ELISA for detectionof antibodies against H9N2 avian influenza viruses. Journal of VirologicalMethods. 2015, doi: 10.1016/j.jviromet. (Corresponding author)

18. Zhao K, Rong G, Hao Y, Yu L, Kang H,Wang X, Wang X, Jin Z, Ren Z, Li Z. IgA response and protectionfollowing nasal vaccination of chickens with Newcastle disease virus DNAvaccine nanoencapsulated with Ag@SiO2 hollow nanoparticles. Sci Rep. 2016 ,6:25720. doi: 10.1038/srep25720. (Corresponding author)

19. Wu X, Shi Y, Yan D, Li X, Yan P, Gao X,Zhang Y, Yu L, Ren C, Li G, Yan L, Teng Q, Li Z. Development of aPCR-Based Reverse Genetics System for an Attenuated Duck Tembusu Virus Strain.PLoS One. 2016, 11(6):e0156579. (Corresponding author)

20. Cui H, Shi Y, Ruan T, Li X, Teng Q,Chen H, Yang J, Liu Q, Li Z. Phylogenetic analysis and pathogenicity ofH3 subtype avian influenza viruses isolated from live poultry markets in China.Sci Rep. 2016, doi: 10.1038/srep27360. (Corresponding author)

21. Yan Liping, Liu Qinfang, Su Xin, TengQiaoyang, Bao Danqi, Che Guangshen, Chen Hongjun, Cui Hongrui, Ruan Ttao, LiXuesong, Li Zejun. Pathogenicity of reassortant H9 influenza viruses withdifferent NA genes in mice and chickens. Veterinary research. 2016,       47(1):67.(Corresponding author)

22. Zhang M, Zhang X, Xu K, Teng Q, Liu Q,Li X, Yang J, Xu J, Chen H, Zhang X, Li Z. Characterization of the Pathogenesisof H10N3, H10N7, and H10N8 Subtype Avian Influenza Viruses Circulating inDucks. Sci Rep. 2006, doi: 10.1038/srep34489. (Corresponding author)

23. Shi Y, Cui H, Wang J, Chi Q, Li X, TengQ, Chen H, Yang J, Liu Q, Li Z. Characterizations of H4 avian influenza virusesisolated from ducks in live poultry markets and farm in Shanghai. Sci Rep. 2016,doi: 10.1038/srep37843. (Corresponding author)

24. Qiaoyang Teng, Dawei Xu, Weixia Shen, Qinfang Liu,Guangyu Rong, Xuesong Li, Liping Yan, Jiangmei Yang, Hongjun Chen, Huhai Yu,Wenjun Ma , Zejun Li. A Single Mutation at Position 190 in HemagglutininEnhances Binding Affinity for Human Type Sialic Acid Receptor and Replicationof H9N2 Avian Influenza Virus in Mice. Journal of Virology. 2016, 90(21):9806-9825. (Corresponding author)

l 参编教材。

1.   《猪流感》,童光志、李泽君主编,2015.8,农业出版社

2.   《禽流感》,参编,2015.8,农业出版社

l 获得授权专利8

1、犬流感重组病毒及其制备方法和应用(ZL201110139528.3),(1);

2、稳定表达高致病力禽流感病毒HA蛋白的MDCK细胞系及其用途(ZL201010106774.4),(1);

3、鸭坦布苏病毒的单克隆抗体、杂交瘤细胞株及其应用(ZL201210030412.0),(1);

4、滕巧泱. 一种鸭黄病毒及其疫苗、试剂盒(ZL201010601050.7),(1);

5、鸭坦布苏病毒弱毒株及其应用(ZL20121027923.6),(1);

6、鉴别鸭坦布苏病毒强毒株和弱毒疫苗株的试剂盒及应用,( ZL201410142794.5),(1);

7、李泽君,李国新,鸭坦布苏病毒E蛋白第三结构域重组蛋白及其应用(ZL201410067680.9),(1);

8Monoclonal antibody against duck Tembusuvirus, hybridoma cell line and application thereof. United States Patent,Patent No.:US9,500,652 B2,(1)。

六、获奖情况

l “禽流感病毒进化、跨种感染及致病力分子机制研究”获国家自然科学奖二等奖,,证书号:2013-Z-105-2-04-R05,2013年;

七、联系方式

通讯地址:上海市闵行区紫月路518 

邮编:200241电话:021-34293446

E-maillizejun@shvri.ac.cn

八、其他

无。

 

 

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